Sentence examples for conservation of the interaction from inspiring English sources
Indeed, this reveals potential conservation of the interaction between the Gli transcription factors and their putative GBS among vertebrates.
10.7554/eLife.01071.010 Figure 2. Mutational analysis of the CPAP:STIL interaction in vitro and conservation of the interaction across species.
In any case, the high conservation of the interaction between miR-511 and MECP2 in both mouse and man makes a specific significance of their interplay very likely.
We then assign a confidence measurement to each interaction based on the level of conservation of the interaction across multiple species and the number of supporting experiments.
Conservation of the interaction surface to other RBM-containing proteins allowed construction of a model for the RPA32C/SMARCAL1-RBM complex.
In addition, the results of MAPPIS are consistent with previous biological studies [ 60], which emphasized the conservation of the interaction of Tyr-55 (E9) with Phe-86 (Im9).
The essential role of XB12 may explain the complete conservation of the interactions centered on XB12 tested in this study.
To determine the degree of conservation of the interactions between proteins involved in defense responses in wheat and rice, we identified and cloned the wheat orthologs of rice genes encoding proteins involved in four well-characterized nodes of the rice interactome and tested their protein-protein interactions using both rice-wheat and wheat-wheat protein pairs.
The finding that other Tudor domain checkpoint mediator proteins bind methylated histones suggests functional evolutionary conservation of the interactions between checkpoint proteins and modified histones; in fact, mammalian 53BP1 and S. pombe Crb2p interact with methylated H4-K20 (Sandets et al, 2004; Botuyan et al, 2006; Du et al, 2006).
This provides a network based explanation to the observed conservation rates that can also help explain why so many biological processes are well conserved despite the lower levels of conservation for the interactions of proteins participating in these processes.
The conservation of this interaction from fission yeast to plants suggests that the well-characterized Mei2 signaling pathway may provide insight into the function of the AMLs.
