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We find that the mir-463 cluster is located in a syntentic region on chromosome X and is most prominently, but not uniquely, expressed in testis in both mouse and rat, indicating conservation of location and expression (Additional file 12, Figure S4A, B) [ 34]. rno-mir-741 is partially conserved; the syntenic mouse miRNA is mmu-mir-741.
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The distributions of words locations in these segments are expected to show clustering, due to positional conservation of locations of cis-regulatory elements [ 23].
In addition, we looked at orthologous genes that showed conservation of chromosomal location and those that showed conserved expression state between the two lineages but not necessarily conservation of chromosomal location.
Conservation of the location of miRNA allowed us to hypothesize as to the location of genes that have not yet been annotated in the goat genome.
The strict conservation of the location and length of this insertion in the archaeal and bacterial families listed in Table S2, in the face of selection pressures over much of the history of the evolution of nitrogenases, argues that a role remains to be found for this additional segment of polypeptide.
During the present study, a comparison of intragenic precursors in human, mouse and cattle with intragenic goat precursors revealed conservation of the location of 43 precursors.
Noteworthy, there is a strong conservation of the location and phase of introns within the PPN GHF5 gene family [ 13].
Conservation of the location of miRNA/host genes throughout a species genome may offer a useful tool for its annotation.
Conservation of genomic location and flanking genes can also be a powerful tool for finding related ncRNAs.
Comparisons of genome structure between Ambystoma and representative fish, reptilian, and mammalian species revealed extensive conservation of gene location at the intra- and inter-chromosomal levels.
In general a good conservation of marker location between SMIBC and the previous four eggplant maps was observed with the exception of six markers (Table 3).
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