Exact(6)
Together with the unambiguous phylogenetic placement of the Melainabacteria within the cyanobacterial radiation based on comparative analysis of highly conserved marker genes (fig. 1), the conservation of features characteristic of Oxyphotobacteria in the Melainabacteria further support a common ancestry and the proposal for a single phylum.
Using known homologs with a low degree of sequence similarity, the user can become familiar with the biological meaning of different aspects of the visualization, including the conservation of features in disordered regions, which often evolve more rapidly than globular regions.
Overall, TMEM16D shows some conservation of features with primates but little with placental mammals or vertebrates.
Detailed comparisons among these and other genomes reveal many differences and unexplained conservation of features that both remain to be understood.
The conservation of features of the putative DNA binding domain across species again emphasizes the evolution of the protein from the core sequence and it is important to test if the DNA binding function is also retained.
Function assignment was carried out based on the conservation of features in the 3D-Jury sequence-template alignment, such as correspondence of predicted and observed secondary structure and conservation of functionally important residues (e.g. residues involved in catalytic activity, in binding to ligands, DNA or other proteins).
Similar(54)
Generally, conservation of phenotypic features between species reflects conserved features of the genome; however, this is evidently not necessarily always the case as demonstrated by the analysis of the tunicate chordate Oikopleura dioica.
Finally, we describe the patterns of conservation of protein features in numerous β-N-acetylhexosaminidase subfamilies and relate these features to the current understanding of GH20 family function, an important exercise given apparent convergence of physiological function of non-orthologous GH20 enzymes in eukaryotes.
Having identified residues and structural features used by the HB3var03 and IT4var07 CIdomainsmains to bind to EPCR, we next assessed the degree of conservation of these features in 737 CIDRα sequences from the EPCR-binding CIDRα1 subclasses.
The ORF exhibited a great homology to Penicillium marneffei and conservation of all features of fungal pectate lyases such as the barrel structure with "eight right-handed parallel β-helix" architecture.
The overall structures of both yeast Uba2ufd and Ubc9 superimpose well on their individual human counterparts, suggesting conservation of fundamental features of Sumo conjugation.
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