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Instead, we found a weaker but still significant enrichment of one-to-one orthologs in developmentally regulated genes (Fig. 4 a), suggesting a certain degree of conservation of developmental gene expression.
In: Evolutionary Conservation of Developmental Mechanisms (A. Spradling, Ed). J. Wiley and Sons, Inc., New York.
D.A. Weisblat, C.J. Wedeen and R.G. Kostriken (1992) Evolutionary conservation of developmental mechanisms: comparisons of annelids and arthropods.
Conservation of protein length and functional domain architecture further assists the assignment of orthology, as does conservation of developmental regulation (Fig. 1c).
Given the molecular conservation of developmental genes and pathways, insights from cichlids are applicable to human facial variation and disease.
Apparently, morphological constraints underlie the conservation of developmental gene expression while embryonic fitness requires the conservation of housekeeping gene expression and the species-specific adjustments of homeostasis gene expression.
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This observation expands our mechanistic understanding of the role of cryptopatches in human GALT genesis and emphasizes the evolutionary conservation of this developmental process.
Marsupials occupy a unique evolutionary niche and can provide important information on the evolution and conservation of mammalian developmental pathways.
We discuss the limited conservation of core developmental and transcriptional programs as a common aspect of animal evolution.
The conservation of hepatobiliary developmental processes at the molecular level and anatomical function between zebrafish and mammals are evident [ 114].
Although there is no doubt that conservation of vascular developmental pathways across species exists, the relative importance of these pathways may differ in each species.
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