Your English writing platform
Discover LudwigExact(5)
We first quantified how many regions showed strong conservation of activity by defining regions as highly conserved if regulatory activity was present in (at a minimum) all ten of the highest-quality placental genomes.
This represents the first engineered inversion of a transmembrane protein with demonstrated conservation of activity and substrate specificity.
We defined the maximum detectable conservation of activity as the number of species in which the DNA could be aligned.
The conservation of activity from yeast to human strongly indicates that the StART-like domains are the active portions of this protein family.
We decided to investigate conservation of activity of our repositioned drug set in an in vivo mouse model of AD for the following reasons.
Similar(55)
Activity-function homology directs our attention to the stability or conservation of activities.
While it is expected that protein activity should be largely conserved within the chordates, the issue of the conservation of the activity of cis-regulatory sequences is open.
It would be interesting to know if the turnover of regulatory mechanisms is associated with as breakdown of synteny, as conserved gene order has been proposed to result from conservation of enhancer activity embedded in neighbouring genes.
Recent results have shown that the ISU of ENVV2 contains immunosuppressive activity [ 11], and we have shown that the ISU of ENVV1 and ENVV2 are preserved, indicating a conservation of immunosuppressive activity through evolution.
These mild conditions for gel formation are compatible with the conservation of enzymatic activity, allowing the enzyme to be present before the microgel formation and thereby enabling us to achieve uniform catalytic activity throughout the gel structure.
To better understand conservation of enhancer activity, we used a comparative genomics approach that integrates temporal expression and epigenetic profiles in an innate immune system.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com