Sentence examples for conservation of active from inspiring English sources
Peptide alignment indicated that, including OsLAP6/OsPKS1, all 27 proteins had high conservation of active sites, product-binding sites, and substrate-binding sites (Additional file 1: Figure S4), implying that these functional sites are evolutionarily conserved in land plants.
Secretion and conservation of active sites in lysozyme g sequences.
Together with conservation of active site catalytic and metal binding residues, the kinetic data establish rTSγ as an l-fuconate dehydratase.
We also discovered that the catalytic efficiencies of members of the subgroup are highly variable, despite conservation of active site residues and structures.
DmeNEP1, in particular, also shares an extremely high conservation of active site residues with CelTO5A8.4, suggesting they are functionally very similar.
The conservation of active liver promoters tracked remarkably closely with the alignability of the underlying DNA, indicating evolutionarily stable promoter activity.
Despite conservation of active-site residues, the Ras-related Rab GTPase activation pathway differs from Ras and between different Rabs.
In addition, SPP can be photolabeled by a γ-secretase transition state analog inhibitor, suggesting a possible conservation of active-site structure within the two enzymes [21], and even Aβ modulators affect SPP activity [22].
The folding of holo-IRP1 follows the pattern of m-aconitase [ 136], despite relatively limited sequence identity (22%), but consistently with the conservation of active-site residues.
It might be expected that some conservation of active-site residues between PHHY and HbpA would be observed, given the formal similarity of their substrates; of the hydrophobic side chains in the active site, for example, Met80 (PHHY) is conserved as Met77 (HbpA).
All PGRPs, as their name implies, are able to bind microbial peptidoglycan specifically but some are believed to have catalytic activity due to the conservation of three active site amino acids [ 23- 25].
