Your English writing platform
Discover LudwigExact(1)
We classified BRCA1/ BRCA2 missense variants into three categories (high conservation, moderate conservation, and low conservation) depending on the number of the species that had a different amino acid from that of the human at the site of variation.
Similar(59)
Additionally, for intergenic and intronic circRNAs, the conservation is moderate, but they still exhibit a remarkable enrichment of conserved nucleotides (Memczak et al., 2013).
Prices will fall when the financial crisis is managed, and retail price increases and conservation help moderate customer demands.
Red indicates high conservation, purple moderate conservation, blue poor conservation.
X. laevis and X. tropicalis had the highest subpocket similarities for CYP2C9 (60 78%); however, the ligand-binding pocket conservation was moderate.
ATX-2 is orthologous to human ataxin 2, which when mutated leads to spinocerebellar ataxia-2 (Sconservationvatisn is moderate over 66% of ATX-2 sequence (blastp e = 2E-26 to human).
Each of the variants was found at a position that is highly conserved across evolution according to the consensus panel of species [Yarham et al., 2012], except for the m.4289T>C variant which shows moderate conservation and the m.7554G>A variant which shows poor conservation (Supp. Fig. S2).
Moreover, even the most conserved category, RNA binding activity (GO 0003723), shows only moderate conservation levels (26%/30%).
Other states continue to protest even the Kasturirangan report's moderate conservation measures.
The alignment of sequences revealed that signal regions exhibited moderate conservation with the exception of Eb11.3 from C. eburneus with homologies of 21.1%, 38.5% and 30.0% to the signal peptides of I1, I2 and I3 superfamily conotoxins, respectively.
However, we observed only moderate conservation of the degree of sex bias for both male- and female-biased genes.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com