Sentence examples for conservation measurements from inspiring English sources

In the previous sections, we have shown that it is necessary to extend the current conservation measurements to consider only the conserved segments in a region.

Conservation measurements have previously been used to support the functional importance of frameshifted splice variants [ 24].

However, a more thorough sequence conservation analysis, involving comprehensive alignments and conservation measurements, has the potential to be much more powerful.

In this study, we demonstrate a gene clustering strategy and utilize this in conjunction with NGS contig assembly, sequence conservation measurements, annotation and expression quantification for de novo assembled transcriptomic data.

Certainly, a long conserved region under the current conservation measurement will also be aligned by CHAOS.

Here we want to estimate the percentage of human functional regions conserved in the mouse based on our new conservation measurement and the functional regions mentioned above.

PhastCons parameters were tuned to produce 5% conserved elements in the genome for the vertebrate conservation measurement (expected length = 45, target coverage = 0.3, rho = 0.31).

The new conservation measurement is similar to the normalized sequence similarity [ 21].

For Drosophila, the conservation scores generated by phastCons were the sequence conservation measurement for the genomes of Drosophila melanogaster and 12 other fly species.

It is thus clear that the current conservation measurement that requires contiguous sequence similarity may claim that 11% (17%*64.8%) of these functional regions are not conserved.

Second, our procedure based on the new conservation measurement provides homologous regions that are more similar to the human regions than the aligned sequences in the genome alignments.