Exact(4)
Because the sequence conservation is poor, it is possible that B. pumilus YwjD functions in a way that enhances its DNA repair activity.
Compared to the weblogos of beta, gamma and lenti LTRs the conservation is poor because it is the broadest model as can also be seen from the average score of the training set in Table 1.
Although the structure and organisation of the Xist gene does not differ greatly between mammals, its overall sequence conservation is poor (Brockdorff et al. 1992; Brown et al. 1992).
A number of contigs with homology to the Ae. aegypti microvillar membrane protein AEG12 were discovered (Table 1, contigs 10 13; Fig. S3) [25] and they also appear to be more distantly related to insect allergens, although sequence conservation is poor.
Similar(56)
However, except for the proximal FAD domain, the degree of motif conservation was poor between the two reductase sequences (pc-foxy1 reductase component and the POR), suggesting that the reductase component of the P450foxy fusion genes has an independent descent and is not duplicated from the native POR gene.
Similarly, the position 55 is reasonably well conserved in fungi XIPs and there is poor conservation in dicot XIPs.
The overall degree of conservation is so poor that further statements about the relationship are difficult.
However, our finding supports those studies that have shown that conservation is a poor predictor of regulatory function [ 46] and is consistent with findings of extensive regulatory gain and loss between lineages, indicating that there is variation in regulatory element positions across evolution [ 47].
It is well known that there is poor conservation of intronic sequences between most organisms.
This may not be surprising as there is poor conservation of cytochromes even among Geobacter species (J. Butler, personal communication).
Amino-acid conservation in loop F is poor and aligning pLGICs and AChBP in this region is difficult.
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