Your English writing platform
Discover LudwigSuggestions(1)
Exact(12)
The linker in RPA70 is an example where the dynamic behavior is conserved even when the sequence conservation is low.
The secondary structure of this region (i.e., helix-turn-helix) is conserved in all classical PTPs, including RPTPγ, although amino acid residue conservation is low.
Although sequence conservation is low N-terminal to the cysteine-flanked core domain between both PrP and ZIP, it should be noted that this region is not well conserved even within orthologs of these protein families, thereby potentially masking evolutionary relationships.
Regions where conservation is low and consistency high may be considered prime targets for phylogenetic reconstruction.
Sequence conservation is low in the interface and in the linker, and NMR changes observed for these residues likely result from indirect effects of IscU binding.
Even in vertebrates, DNA sequences conservation is low and suggests that most lncRNAs are not functional due to insufficient selection pressure.
Similar(48)
For example, although the putative SH2 binding Tyr-SLiM in Histone H3.1 is conserved among sequences from all selected species, their relative conservation was low because of the highly conserved background.
For example, although the two putative SH2 binding Tyr-SLiMs in Histone H3.1 were conserved among sequences from all selected species, their relative conservation was low because of the highly conserved background (see Figure 1A lower panel for a schematic illustration of the background and SLiM specific relative conservation and alignment of Histone H3.1 Y54).
How Ras-like GTPases contribute to this process is not known at present, and while there are a considerable number of candidate signaling GTPases encoded within the genome, the levels of sequence conservation are low and the predicted complexity of subtended signaling pathways rather simple, suggesting novel and/or divergent pathways are operating [19], [42].
Although the P-value of the conservation was low, it was not significant.
Specifically, related sequences were expected to have regions of high conservation, even if global conservation was low.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com