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Exact(7)
The pair (F0, F1) is considered to be a conserved OG pair if c satisfies the conservation criterion (c/ N ≥ NBR_ CONS_ RATIO)).
An energy conservation criterion can be adopted to guide such an extraction of the transformation coefficients.
The reactive test was conducted over 17 days, ensuring that the conservation criterion of the amount of fluid exiting the chamber, set at 10percentt, was well respected.
These observations suggest that the use of synteny information with a relaxed conservation criterion (CONS_RATIO < 1) helps the CoreAligner program to identify robust and reliable core gene sets, although the setting of the CONS_RATIO parameter still remains somewhat arbitrary.
The problem can be avoided by using a relaxed conservation criterion rather than strict universality [ 22], but the problem of how to define a biologically meaningful core still remains.
To distinguish between heterogeneity and relaxation, we relied on the shape conservation criterion introduced and tested elsewhere (32, 33). Figure 3 demonstrates the application of this heterogeneity criterion to the case of Trp130-only HγD-Crys.
Similar(53)
The 25 novel miRNAs belong to 16 novel candidate miRNA families (16 novel miRNAs in total) and to 8 conserved miRNA families, according to our conservation criteria based in previous studies [ 20, 52] (> 90% identity for the mature miRNA and > 60% identity for the precursor).
The fact that the score distribution for conserved and non-conserved candidates is very similar reinforces the idea that conservation criteria alone are not sufficient to identify good precursor candidates.
Of which, 59 miRNAs were conserved across 10 86 species according to our conservation criteria (a blast E value≤10−4 for mature miRNA and precursor).
Of the 25 novel miRNAs identified in this study, 9 belong to conserved miRNA families (existing in at least one more organism) according to the conservation criteria used in this study, and the others are non-conserved (ZF specific).
We next applied the cross-species conservation criteria (see Methods) reasoning that functional Sox10 binding sites are likely conserved across mammalian species.
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