Sentence examples for conservation calculated from inspiring English sources

Because the major problem is the misalignment of nonhomologous residues, the combination of isoforms with the highest protein sequence conservation calculated from the alignment, albeit conservative, may be a good approach to minimize the number of false positives in adaptive selection tests.

Structure predictions from Rosetta were filtered through clustering, and 1000 different structures were obtained and clustered according to a criterion of maximization of common structure conservation (calculated with the in-house algorithm RMSDTT now implemented in VMD).

10.7554/eLife.03532.010 Figure 3. Evolutionary analysis of PapC TD. (A – B ) Sequence conservation calculated with Consurf (Ashkenazy et al., 2010 ) and mapped onto the initial model of the native PapC TD (sim1, t = 0).

We mapped the level of residue conservation (calculated with the evolutionary trace algorithm [ 37]) from the multiple alignment of all NA subtypes to its corresponding position in the structure.

For example, if a pair of orthologous genes in the human and chicken genomes has only a human RefSeq annotation, the chicken exon annotation was inferred by the chicken/human conservation calculated from the VISTA alignment with default parameters of conservation 70 %/100 bp window.

Our new measurement of sequence conservation calculates the sequence similarity based on conserved segments.

Clusters were automatically assigned to four categories ("full", "partial", "split" or "no" conservation), calculating the mean correlation of probesets within and between sub-groups "a" and "b", and comparing the values obtained to a specific threshold T (T = 0.4 in this study).

To examine the relationship between promoter conservation and protein conservation, we calculated the correlation coefficient of promoter conservation (raw alignment score obtained by water) and protein conservation (percentage identity obtained by water).

"Cost-effective Conservation: Calculating Biodiversity and Logging Trade-offs in Southeast Asia," by Brendan Fisher et al, claims to "show that selectively logged forests represent a surprisingly low-cost option for conserving high levels of biodiversity".

In order to identify highly conserved elements and lineage-specific conservation, we calculated the percent identity between the reference sequence and each of the aligned species within each of the conserved elements described above [see Additional file 2].

The conservation value calculated for an individual motif can be visualized graphically.