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Thus, to identify conserved CRMs in the human genome, we need to consider discontiguous sequence similarity, which measures conservation based on the similarity of conserved segments only.
In particular, the interface normal vector is calculated from the level set function while the line constant is determined by enforcing mass conservation based on the volume fraction.
After these results, we recommend a conservation strategy characterised by gene flow consistent with the current population structure, careful seed transfer among maternal lineages (if any), selection of populations for conservation based on the originality of their allelic composition and definition of Management Units (MUs) based on adaptive traits.
Promoters stored in cREMaG were curated for their evolutionary conservation, based on the assumption that functional elements evolve more slowly than nonfunctional elements [12].
Priority areas for conservation based on the highest rates of turnover (colors; see Fig. 3) overlaid on a map of 2005 human population densities (gray scale).
The WeederH algorithm measures conservation based on the sequence conservation as well as the motif occurrence's positions relative to the TSS.
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We calculated miRNA average conservation based on scores obtained from the multiple alignments of 46 vertebrate species using phastCons46way (Siepel et al. 2005).
The study provides a valuable ecological planning resource that prioritizes lands for rural conservation based on their functional contributions to the regional carbon balance.
100-Way Sequence Conservation : based on multiple sequence alignment scores, at the nucleotide level, of 100 vertebrate genomes compared with the human genome.
The green infrastructure (GI) conservation scenario incorporates an open space conservation network based on the functional boundaries of environmentally sensitive areas.
Selection-based techniques generally select notional conservation areas based on the surrogate, then measure representation, or likelihood of representation, of the test features in those areas [e.g. 24], [25], [28].
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