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The induction of those DNA damages will result in mutagenesis and consequently transformation, especially if combined with a deficient apoptotic pathway [ 6, 7].
Consequently, transformation on average is expected to introduce more deleterious mutations than it would remove.
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Unfortunately the fast variables are difficult to analyse (even with the aid of a CAS) and consequently a transformation from fast to slow variables is achieved.
The quality of plasmid DNA is said to be less crucial since impurities resulting from the preparation method might function as carrier and consequently increase transformation efficiency.
Therefore, abnormal expression of CDC25A was implied as one of the potential oncogenic factors leading to dysregulation of cell cycle control and consequently oncogenic transformation.
More likely is that viral hepatitis-associated HCC and ICC are derived from the same cells of origin that have the potential to develop into both the hepatocyte and cholangiocyte lineages, and have long been exposed to the milieu related to genome injury and consequently, tumour transformation (Alison, 2006; Libbrecht, 2006; Nomoto et al, 2006; Roskams, 2006; Zhang et al, 2008).
Extensive use of containerized cargo has caused technological changes in the maritime industry and consequently port transformations.
Beside radical scavenging, the components may influence the structure of the laccase, resulting in insufficient binding of the substrate in the active site, and consequently in less transformation.
While the general impact of ICTs on the travel industry and tourist behaviour has been widely acknowledged [9, 19, 30, 35, 40, 41], an understanding of the impact of ICTs on the nature of city tourism, and consequently on urban transformation and the future development of cities, has received little attention [13].
Ectopic expression of Δp85 and DN-Akt dramatically reduced arsenite-induced Akt activation, and consequently blocked cell transformation upon chronic arsenite exposure in HaCat cells.
Cellular targets for oncogenic transformation consequently differ in number, in their degree of maturation and in their differentiation in mouse tissues compared with their human counterparts.
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