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Treatment of breast cancer cells with high concentration of phosphatidylcholine nanoparticles could affect membrane composition and consequently trafficking of EGFR and signaling through MAPKs.
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In this study, we hypothesized that sound exposure enhances the intra-cochlear trafficking of aminoglycosides, and consequently hair cell uptake of aminoglycosides.
Thus, it is possible that mutations on Asn316 and Phe320 disturb proper trafficking of ABCG1 and, consequently, impair ABCG1-mediated cellular sterol efflux.
Enhancing the ability of chaperones to assist folding might at least partially rescue trafficking of the mutant proteins, and consequently increase function at the PM.
The trafficking of newly synthesized proteins from the trans-Golgi network is also essential for cell polarization, and consequently polarized epithelia show a subapical localization of Golgi apparatus and basal localization of the nucleus (Bryant and Mostov, 2008).
Inhibition of S1046/47 resulted in reduction of EGFR trafficking, consequently abolished activation of EGFR and inhibited upregulation of phosphorylation at tyrosine residues including Y1068.
This reduction would allow a higher road capacity and, consequently, greater traffic fluidity.
The proposed cell design technique will optimize the cell shape according to the user distribution and behavior in the covered area and consequently is expected to reduce the frequent handoff and signaling traffic of location updating from moving users.
This metric gives rise to the design of the distributed energy balanced routing (DEBR) algorithm devised to balance the data traffic of sensor networks in a decentralized manner and consequently prolong the lifetime of the networks.
BE traffic might occupy the bandwidth and consequently insufficient amount of resources is assigned to RT traffic, preventing the provision of required QoS levels.
Containerized traffic of general merchandise is rising.
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