The deacetylated BubR1 can be ubiquitinated by the APC/C and consequently degraded, thereby releasing Cc20 to activate the APC/C against its metaphase substrates, cyclin B and securin.
From genetic studies, we know that in the absence of ethylene perception, the receptors repress ethylene responses by activating CTR1; binding of ethylene inactivates ethylene receptor signalling and CTR1 is consequently inactive, thereby leading to ethylene responses (Zhong and Chang 2012) (Fig. 1).
We confirmed that HPSEC is capable of reducing the complexity of a recalcitrant humic matrix, thereby consequently decreasing the overlapping of NMR signals and improving spectral quality and, hence, signal assignment.
They proposed that transcribed target SNPs alter miRNA gene regulation and, consequently, protein expression, thereby contributing to the likelihood of cancer susceptibility by a novel mechanism of subtle gene regulation [115].
A critical question to be answered is how these phagocytes are triggered to release TGF-β in vivo and thereby consequently contributing to Treg cell generation and immune tolerance.
The real problem lies with the professional chefs and famous cookbook authors and reviewers themselves, who have made their professions into "entertainment, spectacle, news, fashion, science," consequently raising prices and thereby prohibiting those who hate to cook (or who want a break from home cooking) from enjoying a "simple" meal in a nice restaurant.
In cochlear implant patients fibrous tissue will lead to increased electrode impedance and consequently increased power consumption, thereby reducing the efficacy of the device.
However when overexpressed, p21Cip1 forms an inhibitory complex with CYCLIN E/CDK2, leading to G1- and consequently S- phase arrest, thereby forming the G1/S checkpoint [46], [47].
Reducing inflammation and consequently inhibiting structural damage, thereby preserving patient function and quality of life, are the primary goals of rheumatoid arthritis (RA) therapy.
By contrast, the inactivated form of ACCα/β reduces the malonyl-CoA levels and consequently CPT1 is released, thereby promoting the β-oxidation of fatty acids in the mitochondria (Ha et al., 1994; Hardie and Pan, 2002; Lopez-Vinas et al., 2007).
