Sentence examples for consequently suppressing from inspiring English sources

Decreased expression levels of RAF1 demonstrate that PU-H71 inhibition of Hsp90 also inhibits the MAPK signaling pathway, consequently suppressing the transcription of genes associated with cell survival, angiogenesis, proliferation, migration, mitosis, and differentiation.

These findings are consistent with our previous results in which microinjection of recombinant Rad51 protein improved the defective DNA repair capacity of freshly isolated oocytes from AKR/J mice, decreasing the amount of existent DDSBs and consequently suppressing spontaneous apoptosis [7].

Our study findings indicate that the overexpression of IMD in the kidney protects against renal IRI apparently by reducing ERS and consequently suppressing ERS-induced apoptosis.

Its unique mechanism of reducing Sos1 and consequently suppressing Ras Raf MEK ERK activity needs to be further elucidated in future studies.

The role of SIRT6 in co-repressing JUN and consequently suppressing IIS is also likely relevant in this context (Sundaresan et al., 2012).

Here, we show that PCAF can directly acetylate cytoplasmic GLI1 protein at lysine 518, preventing its nuclear translocation and promoter occupancy, and consequently suppressing Hedgehog (Hh) signaling in HCC.

Herein, we performed experiments to test our hypotheses that miR-26a and miR-30c coordinate the inhibition of CTGF expression and consequently suppress EMT in NRK-52E cells.

It is found that the hydrodynamic drag reduces the system response energy and consequently suppresses the motion of the structure.

When the activated ER bound to the affinity region, the molecular lost its swingable function, the electron transfer from the photo-excited dye to the SCE was consequently suppressed.

The first technique has been implemented by increasing the wind turbine blade pitch angle with maximum possible rate to reduce the mechanical extracted wind power and consequently suppress wind generation system acceleration.

Moreover, compound 6k down-regulated the expression of p-GSK-3β (Ser9), β-catenin and c-myc proteins, up-regulated the expression of GSK-3β, consequently, suppressed Wnt/β-catenin signaling pathway and induced the apoptosis of K562 cells.