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Consequently, follow up studies using a larger cohort are needed to address these aspects in detail, such as the impact of different conditions (e.g. time, concentration, temperature, etc)., on quality and integrity of the specimens.
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In reference to the generic construction process, it can be said that Land et al. (2001) made a conscious decision for the first building block concerning rationale and purpose and consequently followed up on it throughout the remainder of the process.
60 cases were consequently lost to follow up and 11 died but provided enough information to be judged by the reference committee; 3 cases were early drop outs (2 women and 1 man) and were therefore not included.
Given that our study implies non-uniform patients' entry and consequently follow-up, this type can be transformed when we suppose the following exponential entry distribution (Lachin and Foulkes, 1986).
Ownership is crucial to ensure legitimacy, consent, and, consequently, follow-up.
It is estimated that dropout rate will be about 20% at the 16 months follow up, consequently at least 70 subjects will need to be recruited.
Consistent with other findings, the SAVE study found that weight loss plateaus between 6 12 months of follow up; consequently, we limited our analysis to 6-month data to avoid instances of weight re-gain in study subjects.
However, a common feedback was that the required time can prolong significantly depending on prior knowledge of the subject and consequently the speed of completing follow up tasks, as well as on efforts put into studying follow up literature: "In the beginning I was fast with solving problems because I have encountered this content before (1h-2h/week).
Patients with lcSSc, however, displayed normal COMP levels both at baseline and at follow up and consequently no significant reduction was observed.
No follow up times were specified, however; consequently, the longevity of the bearing couple cannot be assessed.
Children on prolonged chemoprophylaxis for malaria have reduced immunity to malaria, and consequently higher rates of febrile malaria over long term follow up [25].
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