However, as described above, these changes are rather caused by adaptation phenomena and, consequently, they are not exclusive to steady-state stimulation (i.e. high rate regular stimulation).
Thus, lateral transfer from viruses alone is unlikely to explain the origin of the majority of ORFans in the majority of prokaryotes and consequently, other, not necessarily exclusive, mechanisms are likely to better explain the origin of the increasing number of ORFans.
The heterogeneity of the disease(s) creates a challenge in identifying an exclusive driving force and, consequently, early diagnosis, decision on mode of treatment and prognosis [ 71].
The WGS analysis uncovered progressive evolution of the double-minute chromosome converging on the KIT/PDGFRA/PI3K/mTOR axis, superseding the IDH1 mutation in dominance in a mutually exclusive manner at recurrence, consequently the patient was treated with imatinib.
However, because of the role of CSPG4 in signaling and tumor phenotype, we speculate that its interaction with P-selectin may lead to an exclusive tumor cell activation and consequently survival in circulation.
In 1966, the Virginia Supreme Court, in Loving v. Virginia, upheld the state's ban on interracial marriage -- in part because "marriage has traditionally been subject to state regulation, without federal intervention, and, consequently, the regulation of marriage should be left to exclusive control by the 10th Amendment".
However, the two supposedly older populations in the Middle East have low diversity and consequently the leading edge hypothesis does not provide an exclusive explanation to mtDNA diversity in great reed warblers.
Chile and Peru both claim the Pisco Sour as their national drink, and each asserts exclusive ownership of both pisco and the cocktail; consequently, the Pisco Sour has become a significant and oft-debated topic of Latin American popular culture.
In other words, our workflow detects motifs that represent the consensus of mutually exclusive subsets of pooled sequences, and the motifs consequently represent sequence subsets that could be very different.
All of the kings of the northern kingdom are consequently presented in a bad light because they did not recognize the exclusive legitimacy of the cult in Jerusalem.
