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An enriched presence of STRs in the regulatory region of the calcium signaling machinery has not previously been reported and may have significant consequences for protein expression and function and consequently disease.
As HD diagnosis can be established early in life by genotypic tests, mGluR5 PAMs could be used to slow neuronal loss and, consequently, disease progression.
Age-associated inflammatory conditions as described earlier may promote complement activation and consequently disease states such as Alzheimer's disease, Parkinson's disease, and age-related macular degeneration (McGeer et al 2005).
Using an epidemiological model (without pathogen evolution), Mundt and Brophy (1988) showed that, for a given overall host area, increasing the number of genotype units increases the effectiveness of cultivar mixtures and, consequently, disease control.
The potential peritoneal spaces, the peritoneal reflections forming peritoneal ligaments, mesenteries, omenta, and the natural flow of peritoneal fluid determine the route of spread of intraperitoneal fluid and consequently disease spread within the abdominal cavity.
Although the current data do not support a major role for MDR3 in PSC pathogenesis, gene variants could still play an important role by altering bile composition and thereby the aggressiveness of bile, which could influence the secondary response to any primary (e.g., immune-mediated or ischemic) bile duct injury and consequently disease course [98].
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It's not so much struggle, as disunity, that makes people feel helpless, and hopeless, and consequently, disease-prone.
We report on the importance of an initial correct diagnosis and consequently disease-specific therapy on outcome in 22 consecutive patients with ATRT, treated at the Medical University of Vienna between 1992 and 2012, and propose a new treatment strategy.
Cognitive disorders are frequently underdiagnosed and, consequently, diseases such as dementia are undertreated [ 1].
Therefore, it is possible to suppose that FAM5C may somehow modulate/interfere in cytokine network in diseased periodontal tissues, and consequently impact disease outcome.
Clostridium difficile (CD -associated CD -associated, whicolitisne of the CDACon nosocomial enteric diseases encountered by surgeons, is typically due to the exposure of antibiotics and consequently endemic disease in modern hospitals [1–3].
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