The P. berghei LplA1 gene locus was not only targeted by a knock-in construct but also by the gene replacement construct, which exchanges the PbLplA1 gene with the selectable marker and consequently deletes the PbLplA1 gene.
You will have to format your hard drive, which will consequently delete all previous data stored on your computer including Java.
In most of these methods, prior to prediction, alignment positions showing a gap in the top sequence are deleted, consequently leading to shrinking of the alignment and loss of position-specific information.
The truncated form does not contain the PP1c binding motif, as the first 68 amino acids are deleted; consequently it is expected not to bind the phosphatase.
Thus, if the out-degree of a TF is high, many genes will be affected when the TF is deleted, and consequently should increase fitness pleiotropy.
Streptomyces coelicolor A3(2) represents the model system [ 3] and possesses a complete set of vanRSHAX genes conferring high resistance to vancomycin: consequently a glycopeptide susceptible mutant deleted in the two component regulatory system ΔvanRS was used in our experiments [ 16].
An ~2 MB segment of the telomeric end of MMU12 is deleted [ 23], and consequently seven genes were deleted (Abcb5, Dnah11, Itgb8, Macc1, Sp4, Sp8, and Tmem196) [ 42].
Most nonautonomous families correspond to deleted versions of autonomous elements; consequently their evolutionary affinities are relatively easy to determine.
In Drosophila melanogaster, for instance, around 8% of genes are at least partially duplicated and 2% are at least partially deleted, showing CNP as a common phenomenon and, consequently, an interesting target for genetic plasticity evaluation [ 35].
A deleted mutants of the motor domain of this protein, consequently affects the dynamics of recycling endosomes [33] and of their content, such as the reporter protein followed in this study.
