Sentence examples for consequently cell death from inspiring English sources

If the dut gene is non-functional, the uracil content goes up causing its incorporation into the DNA and consequently cell death [46].

Taken together, these resulted in increased oxidative stress and consequently cell death.

This experiment showed that Roc-A could also inhibit Nutlin-3-induced p53 upregulation and, consequently, cell death.

Mechanistically, the triazole drugs inhibit the synthesis of ergosterol, an essential component of fungal cell membranes, and cause abnormalities in the membrane permeability and consequently cell death [ 6].

However, when not properly controlled, high ROS and RNS levels cause DNA, lipid, and protein damage [ 42], and consequently, cell death may occur [ 43].

Besides, they are also important contributors for intracellular pH maintenance, by partially exporting the protons resultant from the metabolic activity, therefore avoiding intracellular acidification and, consequently, cell death.

This is in line with previous published results by Nygård and coworkers in 2014 who showed that the expression of the d-xylono-γ-lactone lactonase encoding gene xylC led to a rapid conversion of d-xylono-γ-lactone to d-xylonate, decreasing the intracellular pH and, consequently, initiating cell death.

Due to the characteristics of a 3D environment, at some zones within the tissue spheroids some cells are not equally exposed to the environment, impacting in the formation of microenvironments with decreased oxygen, nutrients and soluble factors produced by cellular metabolism leading to the formation of low proliferation areas and consequently necrosis (cell death).

Failure of energy-delivering processes after interruption of brain blood supply results in disturbances of essential ionic gradients, excessive neuronal depolarization releasing large amounts of excitotoxic compounds into the extracellular space, and consequently in cell death via necrosis or apoptotic cascades reflected in impaired sensory, motor and/or cognitive functions [3], [4].

Its activation results in depletion of NAD+ and ATP and consequently in cell death and organ dysfunction [ 10].

Lower concentrations (GI50) of HN2-treated, H2B-GFP-expressing HeLa cells showed the formation of giant cells with enlarged nuclei and, consequently, giant cell death.