Patients with serum sodium between 145 and 150 mmol/l are known to have fewer episodes of intracranial hypertension and consequently a higher risk to develop brain edema.
Based on these findings, a higher exposure to rivaroxaban could be expected in patients with low body weight and, consequently, a higher risk of bleeding with a standard dose.
Due to our inclusion criteria, the overall methodological quality of studies was higher than in the Cochrane Review, which included some older studies without validated dementia diagnoses, less rigorous randomization and allocation schemes and, consequently, a higher risk of bias.
In less than 25% of cases, this deposit leads to a variable degree of lobular inflammation and hepatocellular injury and, consequently, a higher risk of disease progression [ 1, 107].
One possible explanation is that patients who were immunologically compensated (particularly when using HAART), i.e. with high levels of CD4 lymphocytes, are more liable to have traditional metabolic complications such as obesity, metabolic syndrome and hypertension and, consequently, a higher risk of presenting subclinical atherosclerosis [ 37, 38].
In terms of mortality outcomes, 11 trials (16%) did not account for a loss of participant outcome data exceeding 15% and were consequently rated as at a high risk of attrition bias.
14 15 Delays to carotid endarterectomy are therefore associated with a high risk of stroke before surgery, 6 and the benefit of surgery consequently falls rapidly with increasing delay.
Firstly, nurses spend more time and have closer contact with the patients and consequently have a higher risk to induce aggressive behaviour in the patients.
Babies born during the evening or the night may have been exposed to a longer first stage of labour, and consequently have a higher risk of an adverse outcome.
