The evolution of protein families and the consequential evolution of their function are accompanied by the accumulation of mutations at individual sites throughout the protein sequence [ 43].
Together, these data suggest that the CTCF insulator landscape is evolving under two regimes: the first involves a tight conservation of both sequence and binding landscape, and the second shows a dynamic interplay between divergence of specific cis elements and consequential evolution of the CTCF binding trait.
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However, all these mutations are directly induced by environmental stress factors, and those that are adaptive, even if a small minority, are most consequential for evolution.
Consequential asexually driven evolution has resulted in a narrow genetic base, with the crop often lacking resistance to pests and diseases.
Supplemental data from their study provides no indication of positive selection with respect to IGF-I, providing little indication that IGF-I sequence changes have been consequential during human evolution.
However, restricted power in admixture analyses should not restrict studies of hybridization mechanisms, as they raise consequential questions in micro-evolution and behavioral ecology.
In this paper, a model is developed for an elastic perfectly-plastic structural beam system subjected to general pulse-pressure loadings - this may be either impulsive or non-impulsive - which is capable of capturing large non-linear deformation, ductile damage evolution and its consequential failure.
Numerous studies indicate that HGT has been instrumental in producing functionally consequential genomic changes throughout the evolution of prokaryotes (Lerat et al. 2005; Dagan et al. 2008; Treangen and Rocha 2011).
The public discourse around climate and the potential impact of biofuels has played a major, if indirect, role in the evolution of life cycle analysis, and in the development of consequential LCA.
That these interactions would have also been consequential in the origins of chemical evolution has been illustrated, here, by considering the p Ka of the canonical nucleobases, in the context of chemical etiology of nucleic acid structure.
