Sentence examples for consequential alterations from inspiring English sources

The data presented here show that multiple aspects of knee joint patterning and morphogenesis are affected when mechanical stimulation is altered (cell proliferation, cell differentiation and tissue boundaries with consequential alterations to the shape of rudiment epiphyses and the structure of the joint and associated tissues).

So they instinctively embraced a direct and participatory form of democracy which they imported (with consequential alterations) from Switzerland, adding a fourth branch of government to the three existing ones.For much of the 20th century the resulting governance structure did no harm because voter initiatives were used sparingly.

Consequential alterations of CBF are apparent with age, however, physical fitness has been shown to offset these changes [ 1, 15].

Considering the effects of changes in the ecosystem parameters and consequential alterations of the provision of ecosystem services appears important to further our understanding of land-use intensity and for developing indicators of system-level outcomes.

The consequential alteration in the hepatocellular SAM to SAH ratio can compromise activities of many methyltransferases, including protein isoaspartyl methyltransferase (PIMT), to result in an accumulation of damaged proteins bearing isoaspartate residues [9,17 20].

These challenges have served to motivate the application of novel analytical approaches for retrospective studies of DNA methylation that aim to distinguish epigenetic marks that are consequential or reflect alterations to the methylome driven by the tumor itself, from those that are causal or mediate tumor growth and development.

These alterations are especially consequential in experiments involving minutes of exposure to elevated temperatures, such as those used in GC/MS systems, indicating that a significant amount of the spectral data generated in GC/MS experiments may correspond to thermal degradation products.

A third explanation may involve differences among races and regions, as the factors that drive genomic alteration between races are consequential [ 17, 18].

Owing to hundreds of alterations that might be merely consequential to transformation, the use of in vitro model of human cells expressing known oncogenes was proposed as a useful approach to focus on the pathogenic changes displayed by tumors.

Moreover, these alterations were associated with a consequential increase in activated forms of complex ligands [ 24].

Behavior alterations are construed as being consequential to the reported neurological mode of action of this pesticide, further affecting foraging, migration and reproduction [ 30].