This phenomenon could well be caused by copper-catalyzed 'glycoxidation' that mediates formation of advanced glycation end-products (AGEs) and consequential AGE-modification of susceptible amino-acid residues, particularly lysine, arginine, histidine and cysteine, in long-lived fibrous proteins such as connective-tissue collagens [ 5, 50- 54].
If anything, they grow stronger — and more consequential — with age.
Behavioral patterns involving emotional disengagement from and wariness about intimate others (i.e., attachment-related avoidance) may become more consequential with aging when more assistance is needed from others or when loved ones become unavailable (Franz and White 1985).
Daryl Kimball, the executive director of the Washington-based Arms Control Association, described the agreement as among the most complex and consequential of the nuclear age: "[The agreement follows] nearly two years of intense negotiations involving seven nations, including two long-time adversaries, after more than a decade of false starts and missed opportunities.
Foremost are the challenges from the scourge of HIV AIDS, which are proving to be as impactful demographically, thus in other areas of life, as were depletions of populations during the centuries of export enslavement though with consequential differential impacts on age groups.
One of them is not paying sufficient attention to what is ultimately the most consequential story of our age.
In this context, the independent significant effect of PNA on the difference can probably also in part be explained by urinary matrix variation with age and consequential variation in interference with predominantly the Jaffe assay.
So I was sitting in the Theatre of Salt in Florence with my friend Jo discussing golden ages, as one inevitably does when in Florence — it having been the birthplace of that most famous and most consequential of all golden ages, the Renaissance — and I found myself speculating that Silicon Valley's own ongoing golden age is at real risk of ending soon.
With his optimistic bromides and certainty, Bush emerges as a president at once consequential and shallow, physically aged but intellectually and psychologically untouched.
That set a context to frame service growth, planned to grow in line with population growth and ageing, and consequential growth in care workforce demand.
The invisibility of work and workers in the digital age is as consequential as the rise of the assembly line and, later, the service economy.
