Sentence examples for consequent transformation from inspiring English sources

However, when both molecules are expressed, JunB prevents c-Jun DNA binding, transactivation and consequent transformation potential [ 55, 56].

We have previously proposed that the consumption of TGD can reduce the total amount of orally ingested calories via the consequent transformation of digestible substrate to indigestible fiber in the alimentary tract [ 2].

We suggested that the mechanism underlying the reduction in the total amount of orally ingested calories is the consequent transformation of digestible substrate to indigestible fiber in the alimentary tract.

Dietary manipulation of folate has been referred to as a 'double edge sword' because pharmacological depletion of folate by antifolate drugs prevents cancer cell proliferation but might induce genetic and epigenetic damage and consequent transformation in non-cancerous cells.

The consequent transformations can be analyzed in terms of (neo- evolutionary mechaneo- evolutionary

The Drosophila homologue of the CHD7 subfamily, kismet, was identified as a Trithorax gene and kismet mutants have reduced expression of homeotic genes and consequent transformations of body segments to more anterior structures (Daubresse et al., 1999).

Moreover, oncogenic Met mutations in the kinase domain trigger constitutive Met internalisation/recycling, leading to "endosomal signalling" and consequent cell transformation.

An aberrant increase in the level of ROS may result in transient or permanent cellular alterations, such as irreversible oxidative damage on DNA, causing genomic instability and the consequent malignant transformation of the cells (8).

In fact, stem cell-derived exosomes may represent several features of their cells of origin and may play a role in gain-of-function properties, genetic instability, and consequent malignant transformation as well as the induction of reparative programs within injured tissues.

The loss of polarity consequent to transformation by Ras and ErbB2, but not selected isoforms of PI3K, Raf or Src, was associated with a gain of PKCι activity, since knockdown or inhibition of catalytic activity could partially restore a polarized morphology.

Indeed, the transformation consequent of technology in education resembles the dot-com craze in several ramifications.