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In this model, PCs are silenced as a result of excessive depolarization and consequent block of electrogenesis.
The autophagic pathway is impaired in MPS-IIIA mice due to lysosomal accumulation and a consequent block of fusion between lysosomes and autophagosomes (Fraldi et al, 2010; Settembre et al, 2008).
The observed cell cycle arrest and the consequent block of cell proliferation were consistent with an over two-fold increase in p21 in CDDP-treated cells, in which this protein exhibited a mainly nuclear localisation.
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The improved plasticity may be due to the easy initiation of shear bands around the notches, and the consequent blocking effect of notches on the propagation of shear bands, similar to the dislocation mechanism in crystalline materials.
This event was also reported by Liao et al. [ 19], who detected downregulation of cyclin D1 and up-regulation of p27 after HOXB7 gene silencing with consequent blocking G1-S.
These data, associated with our results, highlight the importance of the HS domains present in HER2 to determine trastuzumab interaction with this receptor and the consequent blocking of the cellular pathways that are over-activated in HER2 positive breast cancer cells.
However, the thickness of the aligners and the consequent bite block effect might explain the absence of any change of anterior vertical dimension [37].
Stimulation system determines high frequency stimulation of anatomic-target structure of motor circuit with consequent functional block.
Moreover, persistent sodium currents and consequent depolarization block are thought to facilitate the generation of electrographic seizures (Bikson et al., 2003; Ziburkus et al., 2006; Ullah and Schiff, 2010).
We present a new tool that proceeds further to predict the distribution of scale precipitation in a one-dimensional porous medium and the consequent pore blocking.
The A2-KO mice in our animal house are infertile consequent to the block of spermatogenesis (Chieffi et al., 2002).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com