Ideally, antimalarial treatment should be 100% effective in everyone, but this may not be possible without producing toxicity or recommending a long course of treatment with consequent poor adherence.
6 7 They have poorer quality of life, have loss of physical functioning, and are more likely to experience depression and to be receiving multiple drugs with consequent difficulties with adherence.
This may contribute to improved treatment adherence and consequent clinical outcomes.
This may be explained by possible suboptimal adherence and consequent higher risk of death in children with a poor immune response at 12 months.
C3b binds indiscriminately to pathogens and host cells and its deposition on an antigen mark it for adherence and consequent elimination by phagocytic cells.
Three other qualitative studies among patients in rural areas of the North West, Western Cape and Limpopo provinces have also reported a critical lack of knowledge about the causes of Type 2 diabetes and hypertension, with consequent negative implications for adherence and control [ 17– 17].
While there are some studies from western countries, where there is abundance of high fat and high calorie foods, suggesting increased appetite and the consequent weight gain adversely affecting adherence to antipsychotic medications [ 28], there is paucity of data from low income countries where food is scarce.
Patient-reported outcomes (PRO) are now accepted as important outcomes in assessing the effects of new therapies because PRO may affect treatment adherence [ 1] and consequent clinical outcomes [ 2- 4].
Patient satisfaction predicts medication adherence, medication persistence, and consequent clinical outcomes, including glycaemic control and complications 5– 8; thus, there is a need for a valid, reliable tool assessing a broad range of specific aspects of treatment satisfaction for use in patients who use any available diabetes medications and medication delivery systems.
Treatment satisfaction deserves attention because it may influence treatment adherence [ 15] and consequent clinical outcomes [ 15– 17].
