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Johnson et al. [ 52] suggest that "providing information about a particular issue…can have unintended consequences such as reducing attention about important issues…or increasing focus on only a single corrective action" (page 499).
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Such a situation may lead to a reduction in the natural curvature of the lumbar spine and related adverse consequences, such as reduced amortization properties of the spine, and asymmetric loading of intervertebral discs, which can lead to overloading and degenerative changes in the spine.
The impairment of adrenal or thyroid function by contaminant exposure may occur in the absence of gross toxicologic effects and may be critical to developing individuals, with severe consequences such as reduced growth, reduced cognitive capabilities, and impaired immune function (Schantz and Widholm 2001; Smits et al. 2002; Vos et al. 2000).
Sub-lethal pesticide exposure through wax can have adverse reproductive consequences such as reduced egg laying, early supercedure, increased queen cell rejection, and reduced ovarian weight in queen bees [15], [16].
Osteoporosis was perceived by our patients as a disease leading to severe discomfort and/or disability, and affecting different aspects of personal life with a variety of undesirable consequences, such as chronic pain, reduced physical ability, reduced social activity, poor well-being, and depressed mood.
Megafauna extinction had several potential consequences, such as a scale shift reducing the seed dispersal distances, increasingly clumped spatial patterns, reduced geographic ranges and limited genetic variation and increased among-population structuring.
However, the severe conditions (HCl 6 N, 118 °C, 18 h, or pH 12.5, 95 °C, 20 min) used in chemical hydrolysis can have negative consequences such as racemization, bitter taste, reduced nutritional quality, and poor functionality, resulting in products of lower value, i.e., fertilizer (Chobert et al. 1996).
Feedback may not produce intended outcomes and may even have detrimental consequences, such as decreased motivation and reduced performance.
It is well known that the overuse of antibiotics has several important consequences such as increased treatment costs, reduced clinical efficacy, and above all, the increased emergence of antibiotic-resistant pathogens.
Elevated oxidative stress in the senescent myocardium has several consequences such as enhanced protein oxidation/nitration, reduced bioavailability, lipofuscin formation, activation of inflammatory response, antioxidative stress response, apoptosis, and endoplasmic reticulum (ER) stress [ 29].
Negative attitudes have an undesirable effect on children, leading to negative consequences such as low self-esteem and reduced participation [ 75].
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