This abnormal phosphorylation promotes the release of tau proteins from microtubules, its disassembly, and self-assembly into paired helical filaments (PHFs), a major component of NFTs, and, as a consequence, provokes microtubule disruption [ 188– 191].
But there is an evident tension about how much time to devote to the terrorist acts versus the decade of costs and consequences they provoked.
Nowadays architects are challenged by constantly evolving technology and, in consequence, are provoked to explore undiscovered domains.
It is true that China has the power to destroy the fragile North Korean economy, but Chinese leaders are not willing to confront the consequences of provoking a collapse of central authority in Pyongyang.
The second was that Britain would lose influence if it ceased to be a nuclear power.Today's international terrorists are unlikely to be deterred by nuclear weapons; indeed, they might positively welcome the catastrophic political consequences of provoking a nuclear response by a western country.
Only one of the conference's speakers warned about the consequences of provoking diaspora Muslims.
The global economy is a complex system, and any action taken could have unintended consequences and provoke collateral damage.
54 Lupton argues that there is insufficient recognition of the unintended consequences of provoking disgust in tobacco control campaigns, as disgust can marginalise already vulnerable populations, and create disempowerment rather than choice.
As an important point to consider for future therapies, the authors of a recent study [ 48] raise the intriguing concept that within a tumor, yet unidentified mechanisms of regulated necrosis cause the death of tumor cells within the central core, and in consequence provoke neovascularization, which in turn promotes growth of the residual tumor.
All in all, India's government thought little of the consequences before it provoked an arms race in South Asia.
This all arises from the media frenzy over what we are now calling "coward punches" – a few assaults with tragic consequences that have provoked outrage in certain quarters.
