Modularization usually makes the architecture more complex due to additional interfaces and redundancies that have negative consequences on system performance.
While economic growth has brought prosperity and better living conditions, much of the human impact has had irreversible consequences on environmental systems and destroyed fragile ecosystems and biodiversity.
Sleeping disorders have adverse consequences on multiple systems [ 7] and several studies link sleeping disorders with IGM and increased risk of developing type 2 diabetes, IGT and IR [ 8- 10].
The control laws designed without taking into account the saturation effect may have undesirable consequences on the system stability.
Such unexpected sustained oscillations may reduce the power transfer limit and even result in detrimental consequences on the system equipment.
On the other hand, from the viewpoint of biology, large and sudden environmental disturbance, such as earthquakes, tsunamis, hurricanes, floods, droughts may have important consequences on the system.
Furthermore, from the viewpoint of biology, large and sudden environmental disturbance, such as earthquakes, tsunamis, hurricanes, floods, or droughts may have important consequences on the system.
A detailed quantitative understanding of these processes and their consequences on the system dynamics would also be highly beneficial for the development and the optimization of reprogramming protocols including the generation of induced pluripotent stem (iPS) cells from somatic stem cells or even fully differentiated cells [14], [15], [16], [17], [18].
The absence of this information can have negative consequences on health system functioning.
However, when the use of cortisone was recommended, it was determined that early cortisone exposure, particularly in the postpartum period, had adverse consequences on other organ systems [24], [25].
