On the basis of the insights gained from this study, physicians and nurses provide better information to melanoma patients, in particular to patients who will receive an ALND after tumor-positive SLNB, on QoL consequences of staging and treatment, thus allowing better informed decision making.
The first consequence of stage migration is that it alters the prognostic meaning of the stage.
This example emphasises the importance of analyses using quantitative data and suggests that some recent results, such as a significant independent effect of mammography, observed by Shen et al (2005) might be, at least partially, a consequence of stage migration.
"All charges incurred on matchday as a consequence of staging a match will be passed through at cost.
This is a clear consequence of staging a World Cup in a country the size of a continent - and also of trying to ensure the matches take place at a convenient hour for the European TV audience.
This double-staining enables to document the consequence of stages of neuronal degeneration and removal of neurons, including the accumulation of ingested debris inside the microglial cells and 12(c)).
Furthermore, it has been shown that the floral organ identity factors bind to many of the same sites in the Arabidopsis genome [ 13] and that their global binding patterns undergo changes as flower development progresses, at least in part as a consequence of stage-specific alterations in chromatin accessibility [ 14].
But it would not hurt to spell out exactly what steps outsiders would like the generals to take, how quickly they should be taken, and what the consequences of each stage of compliance or defiance would be.
These differences could be consequences of developmental stage of plant, condition of growth, environment and from minor unavoidable experimental errors during extraction of RNAs and measurement.
A health economics analysis will assess the cost consequences of each stage of the intervention in relation to the primary and secondary outcomes of the study.
