In the scientific literature, it has been suggested that up to 90% of all RRI's develop as a consequence of overuse of body tissue (muscles, tendons and bones) (Lysholm & Wiklander, 1987; Nielsen et al., 2014a).
Unnecessary treatment burden (the activities required of patients to access and use care and navigate complex healthcare systems) is an additional negative consequence of overuse.
Among the environmental factors, food supply chain may be the major source of antibiotic resistance in "naïve" humans as an indirect consequence of overuse of antibiotics for curative and preventative purpose in stock farming and agricultural products.
The C.D.C. has warned that a potential consequence of overusing antibiotics is the development of bacteria resistant to antibiotics.
The contamination by agriculture production is a consequence of overusing pesticides, fertilizers, and other chemical materials.
For example, the impact of migraine-related disability (e.g. MIDAS), the effect on HRQOL (e.g. MS-HRQOL, SF-36), and the risk and consequences of medication overuse should be considered.
A reduction in the length of antibiotic courses is, therefore, a potentially viable strategy to minimize the consequences of antibiotic overuse in critical care, including antibiotic resistance, adverse effects, Clostridium difficile colitis, and costs [ 12].
Closed- and open-ended questions on three topics were included: 1) individual and societal consequences of antibiotic overuse; 2) barriers to improving antibiotic prescribing; and 3) perceived effectiveness of specific intervention components.
A reduction in the length of antibiotic courses in ICU is an important strategy to minimize the consequences of antimicrobial overuse, including antibiotic resistance, Clostridium diarrheae-adverseteffectsrheandadverse effecostsnd costs.
