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In an effort to characterize further the consequences of interfering with S1 cleavage of Drosophila Notch, we examined the subcellular localization of the F2 and F1 mutant Notch proteins and compared their distribution to that of the wild-type receptor.
Next, we wanted to elucidate the functional consequences of interfering with mTOR signaling for PDGF-BB-mediated cellular responses, i.e. survival, migration and proliferation.
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These results suggest that the observed morphological changes are a general consequence of interfering with NMMIIA function.
The consequence of interfering with endogenous Runx2 is a defect in normal osteoblast development or function [73].
Given the known role of SmAQP in such a fundamental process as water movement, the phenotype measured for the SmAQP-suppressed worms (less acid medium, less lactate in the medium) could be an indirect consequence of interfering in the crucial process of water distribution.
The results from this study indicate the complexity of Fe(III -precipitate formatIII -precipitatence oformationring soluthe and its consequences for presenceate structure and phofphate sequestratinterfering
Further, this gene network can undergo concerted epigenetic repression as a consequence of derangement of factor(s) capable of interfering with RARα function.
The Book of Interfering Bodies by Daniel Borzutzky.
The mental health consequences of injuries can interfere with recovery to pre-injury levels of function and long term wellbeing.
The integrated dataset indicated a clear alteration of energy metabolism as a result of sub-lethal copper exposure, with an increased switch to metabolism of stored carbohydrates, presumably as a consequence of copper interfering with mitochondrial function and reducing the amount of energy available from oxidative phosphorylation.
The fact that more than two-thirds of the victims were polydrug opiate abusers also underscores the cumulative effect of psychoactive and CNS depressant substances, amplifying the harmful consequences of opioids and also interfering with heart tissue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com