In reality, design usually involves a number of iterations where the preliminary design is changed as a consequence of feedback from the results of the preliminary efforts, and/or the designers become aware of other possibilities.
The minor decrease in PFR2 and tubulin transcript after the induction of VSG RNAi could be a consequence of feedback mechanisms down-regulating transcripts in cells that are stalled in the cell-cycle and therefore not in need of these structural proteins.
Thus, it would not be fair to say that threshold robustness is a necessary consequence of feedback.
The in vitro preparation presumably reduces or eliminates structured activity in afferent sources of input that could either directly compete with or modulate the consequence of feedback inhibition.
Sectoral and static models cannot adequately describe the interactions between the themes and consequences of system feedback.
These teams are a rare setting in which the consequences of giving feedback to each other is not quite the same as the consequences they will experience when they go to work, where people are much more reticent about giving honest feedback for fear of what it might mean.
For each application of PROMs data, what are the potential obstacles or unintended consequences of PROMs feedback that may prevent, limit of constrain the intervention improving patient care?
However, positive feedback that is merely praise also can reduce autonomous motivation [ 57], a seemingly paradoxical finding that can be understood as the consequences of the feedback in effect becoming an extrinsic (i.e., controlling) motivator.
For each application, we will identify the potential blockages and unintended consequences of PROMs feedback which may prevent or limit the achievement of its intended outcome of improving patient care.
