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The diverse effects of S1P make it difficult to dissect its role in different aspects of mammalian physiology and to predict the in vivo consequences of deficiency in S1P degrading enzymes, including S1PL.
In this study, the consequences of deficiency in any of these two metabolites were investigated by including mutants (cad2-1, vtc1-1 and cad2-1 vtc1-1) which demonstrated multiple genotype-specific effects (for a schematic overview, see Fig. 10).
This review describes the role of vitamin D on immune function, prevalence of vitamin D deficiency in patients with SLE, identify risk factors for deficiency, describe the consequences of deficiency in SLE patients, and review current vitamin D recommendations for patients with SLE.
Similar(57)
20– 22 Simply stated in this context, malnutrition is a suboptimal nutrient status appearing as a consequence of deficiency of nutrients.
yap −/− embryos share phenotypic features of SCRA patients with TEAD1 deficiencies, suggesting that the consequences of Yap deficiency are mediated through Tead.
Consequences of vitamin deficiency Solving the problem of micronutrient deficiency is one of the most urgent tasks in the Kyrgyz Republic, where 'hidden hunger' is common.
Moreover, in studies of T cells and hematopoietic cells, we did not detect any reduction in apoptosis as a consequence of deficiencies of the genes for the individual family members.
Although, we agree that the observed mortality could be, in fact, a consequence of deficiencies in the several other cell compartments and may include crosstalk independent Nfkb2 functions.
The main interest of the mouse system is to exploit the recent generation of transgenic mice and to study the consequence of deficiencies, mutations and conditional expression of gene products.
The consequences of this deficiency of the Lagrangian coordinates are pointed out in connection with numerical computation.
Neonatal lethality prevents a thorough analysis of the consequences of Lrp6 deficiency in the adult mouse.
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