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Consequences of alterations in organ function may be more evident in lungs and brain and less evident in other organs, such as the kidney.
In sum, this study documents sufficient stability and variation in diurnal sAA to warrant future studies on the origins and consequences of alterations in the diurnal rhythm of sAA worthwhile, and proposes guidelines on obtaining reliable measures.
The phosphoserine/threonine proteins down-regulated in PME-1 (or phosphorylated on tyrosine residues, of which there were three examples) likely represent indirect consequences of alterations in PP2A activity in PME mice.
[72], [93], [94], [95], [96], [97], widespread differences in Mn2+ accumulation at 26 hr between DAT KO and WT mice are likely to represent of indirect consequences of alterations in dopaminergic signaling induced directly by deletion of DAT.
Automated systems will enable cognitive scientists to ask questions that are currently difficult to address, and will significantly lower the barrier for developmental neuroscience labs embarking on projects that require them to quantitatively characterize the neurobehavioral consequences of alterations in embryonic development pathways.
10 However, there have been only a limited number of studies investigating the consequences of alterations in microvascular prostanoid synthesis.
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Here, we used Stip1 heterozygous mice (STI1−/+ mice), as well as mice overexpresssing four- to fivefold more STIP1 (STI1TGA mice), to investigate the consequences of alteration of STIP1 levels in vivo.
However, our experimental evidence indicated that A1180V could alter calcium homeostasis as a consequence of alterations in intracellular sodium concentrations, and the former condition might damage myocardium directly and subsequently lead to cardiac dilation [ 10].
The consequence of alterations in the P53 target genes observed in this study are altered growth/proliferation and a potential failure to elicit appropriate responses to apoptotic-inducing stimuli, such as chemotherapy.
Previous study showed that grain chalkiness is occurred as a consequence of alterations in amylopectin structure (Yamakawa et al. 2007).
The prevalence of drug resistance in both clinical and community settings as a consequence of alterations of biosynthetic pathways, enzymes or cell wall architecture is a persistent threat to human health.
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