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Here, we used Stip1 heterozygous mice (STI1−/+ mice), as well as mice overexpresssing four- to fivefold more STIP1 (STI1TGA mice), to investigate the consequences of alteration of STIP1 levels in vivo.
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In sum, this study documents sufficient stability and variation in diurnal sAA to warrant future studies on the origins and consequences of alterations in the diurnal rhythm of sAA worthwhile, and proposes guidelines on obtaining reliable measures.
Consequences of alterations in organ function may be more evident in lungs and brain and less evident in other organs, such as the kidney.
[72], [93], [94], [95], [96], [97], widespread differences in Mn2+ accumulation at 26 hr between DAT KO and WT mice are likely to represent of indirect consequences of alterations in dopaminergic signaling induced directly by deletion of DAT.
The phosphoserine/threonine proteins down-regulated in PME-1 (or phosphorylated on tyrosine residues, of which there were three examples) likely represent indirect consequences of alterations in PP2A activity in PME mice.
10 However, there have been only a limited number of studies investigating the consequences of alterations in microvascular prostanoid synthesis.
The future studies are required for understanding of all biological consequences of alterations in GSK3β-cyclin D3 pathway.
This enables the exploration of the consequences of alterations, e.g., the dose of the ligand or the compliance of the patient, on the disease progression.
Whatever transpires, it cannot be denied that there are important consequences of alterations in leptin homeostasis with those of balance of the autonomic nervous system [ 33].
The pathogenic consequences of alterations in visceral fat mass post transplant is unclear and is a subject of substantial ongoing research.
The increases in glucose uptake and glycolytic pathway activation are consequences of alterations in a range of metabolic enzymes and proteins.
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CEO of Professional Science Editing for Scientists @ prosciediting.com