Sentence examples for consequences of aggregation from inspiring English sources
Instead of directly affecting aggregate formation, HSPA5 most likely compensates for downstream consequences of aggregation and thereby delays disease onset (Gorbatyuk et al., 2012).
Isopods are an ideal model system for the study of these questions; however, surprisingly many gaps in our knowledge still remain and therefore we do not yet truly appreciate the extent of the consequences of aggregation for the physiology, behaviour, or evolution of species [12], [13].
In our studies, we examined the consequence of aggregation on superparamagnetic iron oxide (SPIO) nanoparticle-induced magnetic hyperthermia.
Lower drug release rates have been reported and are a consequence of aggregation of microspheres in the release media (Bain et al. 1999).
One consequence of aggregation, which we documented, is that it may be impossible to disperse the cells in tight aggregates without killing the cells.
In this way we minimized changes in gene expression that are a consequence of aggregation behavior (see Andersen et al., 2014).
It was known that prechondrogenic condensation results from cellular aggregation and differential mitosis, but increased cellular packing in the initiation step of condensation is a consequence of aggregation rather than mitosis.
Our data thus reveal that distinct genetic networks control protein aggregation and the various cellular and organismal consequences of such aggregation.
To explore the consequences of the aggregation of MSAs and PMSAs to MSAs/CMSAs necessitated by the changes in the CPS data, in columns (5) and (6) we keep everything the same as in columns (1) and (2) – in particular, using the data only through 2002 – and the only change we make is to do this aggregation.
Such adaptations may also underlie proteostasis in other cell types, i.e. postmitotic muscle and neuronal cells that are vulnerable to the cytotoxic consequences of protein aggregation.
However, some practical expedients mitigating the adverse consequences of signal aggregation can be envisioned.
