Sentence examples for consequences in the expression from inspiring English sources

The differences in affinity could have important consequences in the expression of sPLA2-V protein.

Several studies showed that gains (or losses) in DNA genomics have consequences in the expression levels of genes in the implicated regions, which are increases or decreased, respectively [ 264– 264].

To evaluate whether the TGF-β1-stimulated JNK activation had a functional consequence in the expression of myofibroblast markers, we preincubated RMF-EG cells with SP600125, specific inhibitor of JNK, prior to TGF-β1 stimulus.

In a recent study we described age-related changes in the expression of the prolyl-4-hydroxylase domain (PHD) 3 and as a consequence in the expression of the hypoxia-inducible factor (HIF -1α transcription factor (KatscHIF -1α2006; Rohrbach etranscription

As a consequence, perturbations in the expression of PRS genes may result in many unexpected cellular events, such as an abnormal increased chitin content and other cell wall alterations [ 33- 35].

To answer the question whether ligand-independent AR binding to the genomic regions exerts functional consequences through changes in the expression level of the targeted genes, we integrated the ChIP-seq data with gene expression profiling data.

24 Despite the potentially dire biological consequences of dysregulation in the expression of Qki, the exact genetic and epigenetic mechanisms governing Qki expression are poorly understood.

In order to analyze the consequences of changes in the expression of enzymes involved in nucleotide metabolism and activation of the DNA damage response in RP-deficient zebrafish, we measured concentrations of dNTPs in Rpl11 mutants and Rps19 morphants.

We present and provide experimental support for a network model (The Transcriptional Override Model; TOM) to account for the unexpected regulatory consequences of modulations in the expression of miRNAs on expression levels of their target mRNAs in ovarian cancer.

To answer the question whether independent Pax8 binding to the genomic regions has functional consequences through changes in the expression level of target genes, the ChIP-Seq data were integrated with the gene expression profiling data.

Consistent with the functional consequences of alterations in the expression of proteins involved in miRNA biogenesis, different studies have highlighted the clinical relevance of defining markers for tumor prognosis and aggressiveness based on the status of the miRNA biogenesis machinery.