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These examples demonstrate the plausibility that perturbations in VSSC function by pyrethroids during development could result in adverse consequences in the developing nervous system.
Group chair Baroness Meacher said that the war on drugs had "disastrous consequences" in the developing world.
We hypothesise that insulin resistance and its consequences in the developing countries may be further elevated with HIV infection itself regardless of antiretroviral therapy.
Several animal models are used to study the mechanisms linking the altered prenatal environment in MO with the increased risk of obesity and other metabolic consequences in the developing offspring [ 52, 53].
Other TCE-induced effects that may have morphologic consequences in the developing heart include disruption of endothelial oxide synthetase, which has a role in endothelial cell proliferation (Ou et al. 2003), and interference with proteins involved in intercellular Ca2+ regulation, which may result in altered blood flow (Caldwell PT et al. 2008, 2010; Collier et al. 2003; Selmin et al. 2008).
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The impacts of BTB infection are manifold: not only the losses due to the depopulation of herds and the social problems of removing cattle from small holdings, but also the vast economic consequences, particularly in the developing countries, that result from herd restrictions, disruptions to trade, and reduced agricultural productivity [ 2].
There are potentially serious consequences for countries in the developing world if the era of ever deepening globalisation is truly over.
None of these studies have investigated the consequences of MRSA in the developing world, yet the effects of disease are considerable (39 ).
One of the consequences of rapid urbanization in the developing world is the continuous growth of slums.
However, Ngn3-null mutant mice die shortly after birth owing to the role of Ngn3 in pancreatic β-cell specification, and the consequence of Ngn3 deletion in the developing hypothalamus upon the behavior of adult mice could not be assessed.
Taken together, these results indicate that a consequence of FREM1 mutation in the developing embryo is a reduction in TIMP1 activation downstream of the PDGF receptor in a pathway mediated by PI3K/AKT and MAPK.
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