Combined with previous evidence of a time-dependent pattern in rate estimates [ 5], this has important consequences for estimating the timescales of recent evolutionary events using molecular clocks [ 4].
In particular, we have found that the number of noncoding substitutions per site (dI) was significantly smaller than the silent substitution rate dS, which appears to be the result of a high proportion of CpG dinucleotides at synonymous sites inflating the mutation rate and this feature may have important consequences for estimating divergence times between species at these sites.
In behavioral genetic studies, the absence of MI may have important consequences for heritability estimates.
Choosing an appropriate variable for which maximum variation is obtained is important, since this can have substantial consequences for the estimates [ 16].
Amplification of RNA-material using primed in-vitro transcription protocols and degradation of RNA during extraction, storage and processing of the samples affects RNA-quality in microarray experiments with consequences for expression estimates and their interpretation.
The current results indicate that attrition related to both baseline and follow-up variables has far worse consequences for regression estimates than attrition that is only related to follow-up variables.
Nevertheless, because the entire study population, responders as well as non-responders, was used in describing the management of chronic non-specific abdominal complaints, the non-response did not have consequences for our estimates of the frequencies of the use of diagnostic modalities, therapeutic interventions and referrals.
As we showed above, this has serious consequences for the estimate of d, and therefore also for the estimate of z.
The measure is the latest turn in a fierce turf war with potential life-or-death consequences for the estimated 68,000 Americans who are currently waiting for a heart, lung, liver, kidney or pancreas.
This test is less essential as rejecting normality of residuals usually does not have any serious consequences for the estimated model.
