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This is partly due to the increasing depths of modern mines, where methane emissions are higher, and also to other mining-related circumstances, such as the increase in production rates and its consequences: difficulties in controlling the increasing methane levels, increasing mechanization, the use of explosives and not paying close attention to methane control systems.
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29 In consequence, difficulties may arise in the attempt to reduce disparities to utilisation of high-volume hospitals, if disparities occur at another level.
The lack of new drug classes is a consequence of difficulties in discovery of new compounds that has persisted for many years.
Decreased social orienting and motivation could, for example, be a consequence of difficulties in processing the incoming social information (e.g., in processing biological movement and actions), rather than their cause.
Also in line with the literature [ 47] (systematic review), the strong association between BMI and walking impairments can simply be explained by low energy expenditure as a consequence of difficulties in moving around, contributing to a higher BMI.
As a consequence, difficulty exists in comparing results, precluding meta-analysis [ 30].
A complete eye exam at least once a year is mandatory since poor vision can lead to social withdrawal, recurrent falls and their consequences and difficulty in measuring blood glucose and managing diabetes treatment.
As a consequence, these unfavorable features result in difficulties in under-represented genome regions, particularly when the sequences are from genomes with base compositions at the extremes of high or low G+C content.
In their consequences, Truman's difficulties in the Middle East were as much domestic as international.
Both consequences increased the difficulties in reconstruction of acetabulum during revision hip arthroplasty.
Also the practical consequences and logistic difficulties in implementing opportunistic screening will need to be addressed.
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