For a normal user, this would be a dead-end with one of two options: ignore the problem and hope nothing bad happens in consequence; or try to repair the operating system using some half-baked recovery method provided by the computer manufacturer or the Windows install disk (assuming they have one).
Perhaps more interestingly, it is seen that properties such as failure consequences and time to repair a damaged system also affect this measure of robustness.
Therefore, though both RpoS and PolIV contribute to survival of problems other than DSEs 29, 44, their roles in mutation during DSE repair are demonstrably not an unavoidable consequence of the need to repair DSEs.
However, from its original proposal in 1975 6 to present (e.g. 8 11), mutagenesis associated with the SOS response has been argued to be an unavoidable consequence of the need to repair DNA, not a property selected in its own right for promoting the ability to evolve.
Here, we have investigated the consequences of a failure to repair DNA damage in motor neurons from DNA repair-deficient Ercc1 Δ/ − mice.
Van Inwagen proposed to repair the Consequence argument by replacing 'N' with 'N*', where 'N*p' says "p and no one can, or ever could, do anything such that if she did it, p might be false".
On a snowy night in February, I went there for a meeting of the town board, the main business of which was the Attorney General's insistence that the town take specific steps to repair the consequences of its negligence.
The Joint Program also supported Burkina Faso to strengthen the capacity of as many as 300 health workers to eliminate FGM and set up a hospital program to repair the consequences of the practice.
It [the budget] really goes out of its way to start repairing the consequences of a decade of neglect.
Sensing the overhang structure, TUTs can employ multiple modes of action and thereby have versatile consequences of either repairing or removing pre-miRNAs depending on the molecular and cellular contexts.
