Sentence examples for consequence of this modification from inspiring English sources

Exact(3)

This, together with heat-sensitivity of the CDC123 mutants, suggests that one consequence of this modification might be to regulate the stability of proteins via the proteasome.

In consequence of this modification, it is not activated by JAK anymore and does not translocate to the nucleus (Xie et al. 2009).

Moreover it will be important to define to what extent the consequence of this modification overlaps with the inhibitory effect of Ser-9 phosphorylation as well as other regulatory mechanisms that target GSK3β [ 43- 45].

Similar(57)

The consequences of this modification for the extraction of a polymer from a porous matrix are explored in detail, and the formal results are explicitly illustrated by means of a specific solution.

In the present work, our goal was to design a new type of nanocapsules, using chitosan chemically modified with poly ethylene glycol) (PEG) (0.5% and 1% pegylation degree) and to investigate the consequences of this modification on the in vitro and in vivo behaviour of the nanocapsules.

The consequences of this modification include: 1) Conjugation of VHL to SUMO1 which alters protein-protein interaction with its substrates; and 2) Competition with other posttranslational modifiers.

Whereas a plethora of information has been obtained regarding the machinery that modifies H3K4 methylation [3], little is known about the physiological consequences of this modification.

Here we have characterized the modification of the C-terminal region of H-Ras by cyPG dienones as well as by other bifunctional cysteine reagents and explored the functional consequences of this modification.

The functional consequences of this modification of CEACAM1 have not yet been systematically addressed.

However, the functional consequences of this modification are as yet unclear [ 31].

SRSF1 associates with the SUMO E2 conjugating enzyme Ubc9 and enhances SUMO conjugation to RNA processing factors but further details on the regulation or consequences of this modification remain to be identified.

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