Sentence examples for consequence of this altered from inspiring English sources

A consequence of this altered metabolic state is the increased production of pyruvate.

However, in the present study, a 21% lower knee abductor moment was found in children with GJH and the long-term consequence of this altered gait pattern is unknown.

As a consequence of this altered behaviour, mechanically evoked antidromic activity may contribute less to the neurogenic component involved in the development of contralateral inflammation than activity occurring spontaneously.

To further explore the possible functional consequences of this altered Foxm1 expression, cytoplasmic and nuclear protein extracts from the whole cochlea of E18.5 and P15 mice were analyzed.

This suggests that achieving a skewed CD8 Treg ratio may be predictive of long-term tumor control, as described recently with other immune-modulating antibodies.[22], [23] We next investigated possible functional consequences of this altered intra-tumor Teff Treg ratio by exploring the effects of GITR ligation on tumor-specific CD8+ effector cells.

The phenotypic consequences of this altered gene expression are, however, beyond the scope of this paper.

The consequences of this altered Ca2+ regulation are likely to be manifold.

Further analyses will be required to better understand the functional and therapeutic consequences of this altered methylation signature.

Neither the mechanism nor the consequences of this altered gene expression is understood at this point, and overall this study raises several questions for which follow-up research will be necessary.

The pathological consequences of this altered process in the context of long-term methylphenidate abuse are still unknown, although accumulation of unnecessary proteins resulting from a defective ubiquitin dependent proteolysis has been shown to contribute to aggregation events, a pathogenic mechanism in several neurobehavioral and neurodegenerative disorders [ 58, 59].

However, it is yet unclear whether these may also represent an indirect consequence of the altered mpt expression (see below).