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The cellular response thus elicited is a consequence of this alteration in the gene expression profile.
As a consequence of this alteration, the glucose consumption and the lactate production (just after 24 h) significantly increased, whilst G6PDH and GR activity were not significantly modified with respect to control cells.
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In abnormal conditions, low levels of leptin at birth are seen in small for gestational age infants [52], but the neurodevelopmental consequences of this alteration have not been evaluated.
The consequences of this alteration in diastolic Ca2+ level at the point of action potential-induced Ca2+ release must be considered when assessing the effect of K201 on the Ca2+ transient amplitude.
Since γc cytokines trigger an increase in the expression of Tim-3 and PD-1 on T cells, we performed experiments to observe the functional consequences of this alteration.
TP53 was again identified as the most commonly mutated gene in HNSCC and, while mutant TP53 has been associated with poor survival, the most important biologic consequences of this alteration have been elusive.
However, TCR re-expression could be altered as a consequence of the alteration in CD28 and its signalling.
It is thus possible that HIBM may be a consequence of the alteration of another yet unknown role of GNE.
As a consequence of these alterations dynamic characteristics of the beam are changed revealing a set of frequency band gaps.
Alterations in the tumour suppressor p53 have been reported in tumour-associated stromal cells; however, the consequence of these alterations has not been elucidated.
The functional consequence on the ST7 protein of this alteration is not known (Thomas et al, 2001).
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