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A shared consequence of the regulatory mutations was the reduction in RpoS levels, as shown in figure 2 A and figure 3 F.
Our model elucidates that not only the condition-response effect but also the noise-propagation effect is often a functional consequence of the regulatory interaction; that is, instead of being just an unavoidable side-effect of regulation, noise-propagation is often beneficial and can be considered to act as a rudimentary form of regulation.
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Then we turn to the empirical body of the paper, in which we observe that Dutch government is responding to the negative consequences of the regulatory state by taking major decisions with regard to the entrance to the legal system.
Finally, our results provide a global picture of biochemical and physiological consequences of the regulatory networks induced at 10°C.
They may also be a consequence of the depleted regulatory function of Pdro on RhoA GTPase activation [9], as the Rho GTPases are thought to exert mutual regulation to coordinate cytoskeletal behavior [25].
Therefore, linkage between different types of variability is mechanistically a consequence of the sophisticated regulatory strategy involving promoter nucleosomes and TATA boxes.
The increase in mRNA levels of most of the repair system genes may be a consequence of the global regulatory mechanism rather than the result of a single transcription factor.
The increased organizational complexity of the eukaryotic origin definition and MCM recruitment system is likely a consequence of the increased regulatory demands imposed by the large number of replication origins found in eukaryotic chromosomes (Diffley, 2011).
Probably, this difference is a consequence of the enhanced regulatory mechanisms in B. subtilis which could have been developed for a systematic recruitment of metabolic signals to improve the response or to switch between vegetative and spore life cycle.
Conversely, where alleles are balanced in genomic DNA, the identification of allelic expression imbalance (AEI) in tumours, but not matched normal tissue (Smith et al, 2004), indicates that the increased level of expression for a given candidate may not be a consequence of the normal regulatory processes governing the activity of that gene.
These strategies could have serious consequences for the regulatory process of the health sector.
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CEO of Professional Science Editing for Scientists @ prosciediting.com