Sentence examples for consequence of the defect from inspiring English sources

The consequence of the defect in GPVI receptor signalling on aggregate formation on a collagen surface at arteriolar shear was investigated.

Hyperglycemic-hyperinsulinemic clamp analysis of human type 2 diabetic patients has revealed that insulin resistance in muscle is a direct consequence of the defect in glucose transport [ 11– 13].

3) Increased p53 binding upon loss of G9a may be an indirect consequence of the defect in enhancer repression, perhaps resulting in the increased enhancer accessibility- did the authors consider looking at chromatin accessibility measurements such as ATAC, DNase or FAIRE?

Our own IHC studies suggest that type II collagen is not co-retained with mutant COMP in the rER, however, there were clear differences in the localization of type II collagen in the ECM, which may be a direct consequence of the defect in trafficking of COMP, matrilin-3, and type IX collagen and/or the reduced levels of these proteins in the cartilage ECM (Supp. Fig. S4).

This is probably a consequence of the defects in the composition and function of the bacterial membrane and cell wall.

The failure of preplate neurons to polarize in the absence of RELN or SFK signaling could be a consequence of the defects in radial glial morphology previously described in reeler or a secondary consequence of the migratory defects observed in neurons of the reeler ectopic cortical plate.

In relation to recent publications on the same subject, we have extended the characterization of the model up to 11 months of age, a point at which the neurological consequences of the defect are already clearly visible.

If these findings should be taken into account when discussing considering the use of MSC-based therapies in an autologous setting, functional experiments must be designed to validate the consequences of the defect of patients' MSC described in this in vitro study.

Bone histomorphometry was performed to further characterize the bone phenotype and to find out whether it is a consequence of the cartilage defect or a primary bone defect.

These later selection filters, however, screen for cellular performance, and molecular faults will go unnoticed if the phenotypic consequences of the defects are efficiently compensated or only manifest later during development.

An extremely high ID/IG ratio for rGO of 2.8 (532 nm) was observed in the Raman spectrum as a consequence of the lower defect density in GO.